PaintScape™ in situ, single-cell direct visualization of 3D genome organization in ER+ and HER2+ breast cancer cell lines
PaintScape System and CosMx WTX enables in situ direct visualization of 3D genome changes and spatial gene expression in single breast cancer cells
PaintScape™ in situ single cell spatial multiomic profiling of 3D genome organization in fresh frozen glioblastoma tissue
PaintScape™ in situ single cell spatial multiomic profiling of 3D genome organization in fresh frozen (FF) colorectal carcinoma tissue
PaintScape integrated 3D genome, transcriptome, and proteomic assays simultaneously observed genome architecture and transcriptional activity at single-cell resolution
A combined approach using PaintScape and CosMx revealed how disruptions in genome organization drive disease mechanisms in ER⁺ breast cancer by linking altered chromatin topology to dysregulated expression of key oncogenic pathway genes
PaintScape™ directly visualized and characterized in situ structural and conformational changes of oncogenic pathway genes in cell lines from different stages of breast cancer (BC) progression
