PaintScape™ in situ single cell spatial multiomic profiling of 3D genome organization in fresh frozen (FF) colorectal carcinoma tissue
The PaintScape™ multiomic tissue protocol enabled direct, in situ visualization of genome organization in FF human glioblastoma tumor microenvironment cells
PaintScape integrated 3D genome, transcriptome, and proteomic assays simultaneously observed genome architecture and transcriptional activity at single-cell resolution
A combined approach using PaintScape and CosMx revealed how disruptions in genome organization drive disease mechanisms in ER⁺ breast cancer by linking altered chromatin topology to dysregulated expression of key oncogenic pathway genes
